Using Blood Pressure Medications in a Preventative Role for Left Ventricular Hypertrophy.

This is a potentially very deep hole to open, but I have been meaning to broach the subject for some time… so lets open her up.

The effect of anabolic androgenic steroids on the cardiovascular system has been well described in the literature. The use of Anabolic Androgenic Steroids (AAS) has been linked to underlying a number of cardiac conditions

AAS like other endogenous steroids influence left ventricular hypertrophic response through the androgen receptor.

Androgen receptors are found on skeletal muscle and also on cardiac myocytes. They cause alterations in heart structure, including left ventricular hypertrophy, dilation which can cause impaired contraction and relaxation

Anabolic steroids can induce an unfavorable enlargement and thickening of the left ventricle, which loses its diastolic properties with the mass increase.

AAS can also cause hypertension, dyslipidemia, and impaired fasting glucose.

There is a case to be made for the use of ACE Inhibitors and ARBs in the preventing Left Ventricular Hypertrophy by
Hypertensive Patients


I am surprised that this is not a more common practice in AAS users.. in a preventative sense.

This conversation has the potential to spread into many ” separate discussions” from treatment of Steroid Induced LVH ( there case studies to look at ) to prevention.. to which ACE or ARB is best suited to the task and at what dosage.. along with the very practical ” what additional risks” if any would deployment present.

Anyone with initial comments.. most welcome.

Victor Black

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