Nandrolone is an Aldosterone Agonist

Nandrolone is an Aldosterone Agonist

If you have ever made the mistake of allowing yourself to be drawn into a discussion with a “Nandrolone only” zealot you will know that they love to wheel out all manner of Bro Science justifications for not using Testosterone as a Base in PED cycles

Often they will claim because of the lower rate of conversion to Estrogen you will hold less water than when using Testosterone.

Don’t get me wrong, I think Nandrolone is a fabulous compound and it is justified in anyone consideration as an offseason compound.

However use it at Supraphyisologiocal dosages and your Aldosterone levels go up just like with Testosterone 

Na+ and K+ concentration also rose from the initial period of administration to the terminal phase of study, no surprises there



Halotestin (Fluoxymesterone) – Don’t believe everything you read on the Internet

Halotestin (Fluoxymesterone) sold under the Brand name Androxy.

Don’t believe everything you read on the Internet

Like virtually everyone in our community initially when I first wanted to learn more about PIEDs I started by reading the few books that where available on the subject. Later as the Internet developed we felt blessed by the emergence of websites that took up that role ( or at least complimented various books ) and for a time I felt rather confident that I understood with a fair degree of expertise these Compounds, the risks attached to their use and ” how to use them”.. based on my reading of and understanding of these resources.

But eventually, as I dug deeper and deeper I came to be confused by noticing a difference between what you read on these sites and what you read in the Clinical Literature from the Research Community.

As I am 30 days out from the first competition of Season A 2019 and in another 15 days I will start to use Halotestin, let me offer this drug as an example.

Go looking for information on Halotestin on one or more of the more popular AAS websites today and you will find snippets of information like this.


On the Estrogenic Side-effects on Halotestin

” Although a testosterone derived anabolic steroid, Halotestin does not aromatize and will not produce estrogenic related side effects. Water retention and gynecomastia are impossible with this steroid. “

that word jumps out ” impossible” – strong words

But ok ” no water retention” ” ” no gyno” – impossible.. noted

On the Estrogenic Side-effects on Halotestin

” Because of its chemical modifications mentioned in the introduction to this profile, Halotestin side effects do not include any measure of Estrogenic activity or Estrogen-related side effects what so ever at any dose.

It is unable to interact with the aromatase enzyme in order to form Estrogens through the conversion process, and therefore all of the side effects normally associated with Estrogen should not present themselves from Halotestin alone.

Estrogenic side effects include the following: water retention and bloating, blood pressure elevations (as a result of the water retention), increased possible fat retention/gain, and ” gynecomastia.

This time ” no X side effects what so ever at any dose ” – noted

What about Bill Llewellyn’ Anabolic Guide

On the Estrogenic Side-effects on Halotestin

Fluoxymesterone is not aromatized by the body, and is not measurably estrogenic. An anti-estrogen is not necessary when using this steroid, as gynecomastia should not be a concern even among sensitive individuals.

OK, so what I read here in general is Halotestin cant cause Gyno or water retention right ?

Do you agree ? Is that what you read ?

Well why then does the Product insert that comes with the Drugs from Pharmaceutical Manufacturers state

” Due to sodium and water retention, edema with or without congestive heart failure may be a serious complication in patients with preexisting cardiac, renal, or hepatic disease. In addition to discontinuation of the drug, diuretic therapy may be required. If the administration of fluoxymesterone is restarted, a lower dosage should be used.”


” Gynecomastia frequently develops and occasionally persists in patients being treated for hypogonadism. “

There must be a reason for this. Right ?

The manufacturers inserts says possible

Water Retention and Gynocomastia

Learning Point

Use of fluoxymesterone, can absolutely lead to irreversible and persistent gynaecomastia and water rentention 100 percent !

Certain adverse effects have been associated with this drug. Among them are included hepatotoxicity, psychological disturbances, virilization, reduced spermatogenesis, gynaecomastia and cardiovascular complications.

The underlying molecular mechanisms of the side effects remain unknown. Therapeutic doses of testosterone can be aromatized to oestrogen peripherally and cause gynaecomastia. Non-aromatisable androgens such as methyltestosterone and dihydrotestosterone can also cause gynaecomastia via other unknown mechanisms.

Read that again.

Non-aromatisable androgens such as methyltestosterone and dihydrotestosterone can also cause gynaecomastia via other unknown mechanisms, I will explain the water rentention in another post cause that one we understand ” why”

Case Study ? Sure here is one..

bcr-2014-207474 (2)

Biochemical and hormonal tests to rule out pathological causes of gynaecomastia were normal (table 1). Breast mammography showed normal glandular breast and normal breast tissue on biopsy. Abdominal ultrasound revealed normal liver, pancreas, kidneys and prostate. Based on the clinical history, temporal relationship between drug initiation and appearance of gynaecomastia and the absence of pathological causes, the patient was diagnosed to have drug-induced (fluoxymesterone) gynaecomastia.

Takeways for the Bros

You can absolutely get Gyno and Water Retention from Halotestin ” conditionally yes .. all the evidence support this.. conditionally? yes sure.. but hey everything we do is ” conditional.. all of it.

2. If all your knowledge comes from ” Steroid websites”

I guarantee when you open your mouth to speak.. some of it its going to be ” Bro Science” ..

Victor Black