Androgens and PSA levels as a Prostate Health Marker
Had an interesting call with a Young Man yesterday re PSA
Understand the evidence we have that elevated Androgen do not deleteriously affect the Prostate of a Healthy Young Man, today is overwhelming.
Not Prostate Volume of Health not even PSA reading
Here we see the PSA levels at 100, 200 and 500mg Testosterone a week.. nada.. no significant difference in PSA
Not Prostate Volume of Health not even PSA reading
Yes there are tons of things that can affect the PSA levels in a Healthy Male but elevating to moderate levels of Androgens is not at the top of the suspect list.. ” sexual activity” is far more likely the cause of that.. if you value PSA levels as markers.. no ejaculation for 24 – 48 hours before PSA testing
High dose Test being used to ” treat” Prostate Cancer ?
The majority of treatment of advanced prostate cancer has focused almost exclusively on inhibiting androgen receptor signaling
Recently Scienticts have been exploring the use of treatment with excess androgens, a strategy he called ‘‘hormone interference’ and the mechanisms
underlying the antitumor effects of androgens.
The seemingly paradoxical ability of supraphysiologic androgen levels to inhibit prostate cancer growth has been demonstrated in multiple
in vitro and in vivo studies.
In addition, a number of case series recounting the benefits of testosterone supplementation in prostate cancer patients have peppered the literature for more than half a century
These findings have renewed interest in exploring high-dose T as a therapeutic strategy for men with advanced prostate cancer, and have provided the impetus for the development of a series of prospective studies testing intermittent highdose T in the clinic, a therapeutic strategy that has been termed bipolar androgen therapy (BAT).
