Telmisartan – a ARB and a Peroxisome Proliferator Receptor Angonist

Telmisartan – a ARB and a Peroxisome Proliferator Receptor Angonist

If you follow my posts you will know I am constantly telling guys

Don’t take so much of a Drug that you need a second Prescription Medication that offers nothing towards out goals and yet come with a long list of their own problems just so you can tolerate the side effects of the first

Responsible PED users should not need Ais, DHT Blockers or Prolactin Modulators like Caber – none

Often the consequences of these drugs are worse than the consequences of the drugs your taking in the first place haha

Learn how to use PEDS in such as way that you don’t need to take drugs just so you can take drugs so you can take drugs..

Now the one exception to the rule IMO is the use of a Blood Pressure Medication

I have written many posts about all the many benefits of ARBs

I am not a fan of ACE Inhibitors myself and the primary reason is I do use Trenbolone and Trenbolone and ACE Inhibitors don’t play well together.

So there are 8 ARBs for you to choose from

Which one is of most interest to me ?


For this is not only an angiotensin II type 1 receptor blocker ( ARB ) it’s also has peroxisome proliferator receptor γ-stimulating activity

and the consequences of that are far-ranging

From its consideration as an Anti-obesity Drug to its function in a possible role in improving cognitive function

From improving insulin sensitivity to being Kidney protective

This a very interesting and almost unheard of drug in our community

This is not a drug that you should place in the first part of our discussion – ie drugs you take so you can take drugs

Hell if you are an older man you might consider using this even if your Natural, maybe

Takeway here

This is not just a BP med.

The PPAR-g-modulating activity of Telemarsartan has been shown in Ab-injected mice treated with telmisartan showed an improvement in cognitive decline, enhancement of CBF, and attenuation of an Ab-induced increase in the expression of cytokine.

So whilst an ACE-Inhibitor like Ramipril might be making your Trenbolone side effects worse

Telemarsaratan might, via its PPAR-g-modulating activity be working for us when we expose ourselves to high levels of AAS, maybe…

Victor Black

Clients with high Blood Pressure are very common

I know this might sound overdramatic but there are times.. moments in time when I feel like I have helped someone from a future of really bad health problems and feel very happy for them

This is a client I started working with the end of May

I told him to go buy a BP monitor and a Blood Glucose Monitor

His Blood Pressure was just too high.. and he was not even ” on cycle” .. imagine if he went on cycle from here ?

Just a few weeks of ” eating right” .. and now we are getting back down to where we can talk about enhancement practices

No BP meds here.. just diet changes

Yes I know I can be ” bullish’ at times.. but I care about you..

Victor Black

Using Blood Pressure Medications in a Preventative Role for Left Ventricular Hypertrophy.

Using Blood Pressure Medications in a Preventative Role for Left Ventricular Hypertrophy.

This is a potentially very deep hole to open, but I have been meaning to broach the subject for some time… so lets open her up.

The effect of anabolic androgenic steroids on the cardiovascular system has been well described in the literature. The use of Anabolic Androgenic Steroids (AAS) has been linked to underlying a number of cardiac conditions

AAS like other endogenous steroids influence left ventricular hypertrophic response through the androgen receptor.

Androgen receptors are found on skeletal muscle and also on cardiac myocytes. They cause alterations in heart structure, including left ventricular hypertrophy, dilation which can cause impaired contraction and relaxation

Anabolic steroids can induce an unfavorable enlargement and thickening of the left ventricle, which loses its diastolic properties with the mass increase.

AAS can also cause hypertension, dyslipidemia, and impaired fasting glucose.

There is a case to be made for the use of ACE Inhibitors and ARBs in the preventing Left Ventricular Hypertrophy by
Hypertensive Patients

I am surprised that this is not a more common practice in AAS users.. in a preventative sense.

This conversation has the potential to spread into many ” separate discussions” from treatment of Steroid Induced LVH ( there case studies to look at ) to prevention.. to which ACE or ARB is best suited to the task and at what dosage.. along with the very practical ” what additional risks” if any would deployment present.

Anyone with initial comments.. most welcome.

Victor Black

2 weeks into my competition cycle for 2019 and my Blood Pressure is moving up.

Blood Pressure ( again )

I believe in full transparency.

2 weeks into my competition cycle for 2019 and my Blood Pressure is moving up.

Elevated BP and Elevated Hematocrit is simply a reality of the types and dosages of drugs we use during periods of ” elevated risk” ie pre contest

What is important here is we don’t stick our head in the sand and pretend its not here.. just step up and address it.

How to take your Blood Pressure..

This might seem a little ” Captain Obvious” but I know it has helped some guys in the past.. because this is serious business with due regard to our health when using PEDs..

You should sit quietly for a minute or two before measuring..

Dont talk to someone else whilst measuring..

Put both feet flat on the floor.

Support your back on a Chair with a Back support..

Make sure your arm is supported the effort of holding your arm in position will change the reading..

Make sure you have a cuff large enough for your arm ( a small cuffs mean elevated/incorrect readings )

If your cuff cant fit your Arm you can do what they do for obese people and that is take at the wrist.. not ideal but it is what it is.. eventually you should buy an XXL cuff..

Make sure that the cuff is at heart level.. this is especially true if you take BP at the wrist.. try taking your BP just 6″ above or below heart level and you will see this changes the reading..

Measure the readings in both arms – a large differential might indicate an underlying issue.. a small variation is normal..

Use the side that has the highest reading in the future

If you taking BP medication take the reading before you admin the Medicine ..

Victor Black